Subject: R&D

Developing and Optimizing of Roll Compacted Granulations for Tablets

Granulating is the most popular way to prepare materials for tableting. Many excipients and actives used in modern direct compression processes are granulated. The granulation process, using only pressure for particle size enlargement, is dry granulation (Roll compaction (RC)). The RC process, even though simple in principle, can be quite complex. Besides proper machine setup,… Continue reading Developing and Optimizing of Roll Compacted Granulations for Tablets

Detergents and Cleaning Products

Like other industries, the cleaning products industry has had to adapt to the changes forced on it by the COVID-19 pandemic. The sector has a unique role in ensuring society remains clean, healthy, and free from infections. Thus, our industry has suffered less than most. We will review how the industry has developed to its… Continue reading Detergents and Cleaning Products

An Introduction to Oral Solid Dosage Form

The most common pharmaceutical dosage is the oral solid dosage form, which includes both tablets and capsules. There are many different ways to manufacture these products, starting with the appropriate selection of excipients all the way through the production of the finished product. Ultimately, the successful production of a tablet or capsule is dependent upon… Continue reading An Introduction to Oral Solid Dosage Form

Sunscreen Basics

In the Cosmetic and Personal care market, almost everyday creams claim to offer a sun protection factor or SPF, and body products for summer holidays claim high SPF numbers. In the U.S. the sun-filters (UV absorbing molecules) are listed on a positive list, they are considered drugs that can be sold over the counter (OTC),… Continue reading Sunscreen Basics

Introduction to Softgel Manufacturing and Controls

Softgel dosage forms represent a modern take on the traditional tablet product, the most common type of pharmaceutical products produced. In the patient’s hand, a softgel can seem like a simple product not knowing there are numerous complexities that go into its manufacture. But for the manufacturer, without a clear understanding of the science behind… Continue reading Introduction to Softgel Manufacturing and Controls

Introduction to Tablet Manufacturing by the Direct Compression Process

Solid oral dosage forms such as tablets and capsules represent the most common type of pharmaceutical products produced. In the patient’s hand, a tablet can seem like a simple product not knowing there are numerous complexities that go into its manufacture. But for the manufacturer, without a clear understanding of the science behind the ingredients… Continue reading Introduction to Tablet Manufacturing by the Direct Compression Process

Microbiology for the Non-Microbiologist

Appropriate as a GMP Microbiological Refresher With the increasing number of Regulatory Actions throughout North America to include Form FDA 483s and Warning Letters for both Active Pharmaceutical Ingredients (APIs) and finished products, it has become increasingly important for companies and individuals manufacturing both non-sterile and sterile final products, to have a basic understanding of… Continue reading Microbiology for the Non-Microbiologist

Lyophilization Formulation and Process Development

Lyophilization is a very common technique used in preparing finished drug products. Yet there are many problems that can arise in production if the process has not been carefully developed. Without a good understanding of the development of this formulation and the process, these problems can readily occur. This accredited course will provide a brief… Continue reading Lyophilization Formulation and Process Development

Navigating Digital Marketing and Clinical Claims in the Cosmetic Industry

The rules and regulations regarding supporting advertising claims for cosmetics have not changed. A claim cannot represent a cosmetic as a drug; the basis for claim support still needs to be consumer perceptible. However, the new vectors for sales and marketing via social media and website sales have brought forth a new paradigm for developing… Continue reading Navigating Digital Marketing and Clinical Claims in the Cosmetic Industry

Basic FDA GLP Training

Before any drug can be used on humans, it must first be proven to be safe through testing on animal models. The FDA Good Laboratory Practice (GLP) regulations were implemented in 1979 in response to the inadequate quality and scientific rigor of nonclinical (toxicology) studies. The FDA GLPs outline the requirements for conducting nonclinical studies… Continue reading Basic FDA GLP Training