Optimization of Powders for Flowability

There are several metrics that formulators use to quantify the flowability of powder blends, including angle of repose, Carr and Hausner ratios, FFC, and flow energies. They all have one thing in common: none will predict whether or not a powder will flow in a hopper. Frequently, powders that are deemed easy flowing exhibit flow… Continue reading Optimization of Powders for Flowability

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Good Manufacturing Practices (GMP) for Foods

This course is designed to provide participants with comprehensive knowledge and practical skills in developing an effective Food Safety Program. The course covers the essential elements of food safety, including good manufacturing practices, and Hazard Analysis and Critical Control Points (HACCP) programs, specifically tailored for food manufacturing facilities, and sanitary design. The course will explore the fundamental… Continue reading Good Manufacturing Practices (GMP) for Foods

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Ethylene Oxide: Product Adoption and Parametric Release

Ethylene Oxide (ETO) Sterilization is a critical process for medical devices, which might include pharmaceuticals and the food industry. Today, the challenge is to understand product adoption during material changes to simplify and have a more robust product validation process based on product families. Another benefit is to have a better understanding on Parametric Release… Continue reading Ethylene Oxide: Product Adoption and Parametric Release

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Developing and Optimizing of Roll Compacted Granulations for Tablets

Granulating is the most popular way to prepare materials for tableting. Many excipients and actives used in modern direct compression processes are granulated. The granulation process, using only pressure for particle size enlargement, is dry granulation (Roll compaction (RC)). The RC process, even though simple in principle, can be quite complex. Besides proper machine setup,… Continue reading Developing and Optimizing of Roll Compacted Granulations for Tablets

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Chocolate and Cocoa Processing

The focus of this training program is chocolate and cocoa processing. The course will guide you through the entire process, from cocoa beans to finished products. The program will emphasize the fundamental principles of chocolate and cocoa processing, including raw materials, finished products, equipment, facilities, and warehouse layouts. Upon completion of this course, you will be able… Continue reading Chocolate and Cocoa Processing

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An Introduction to Oral Solid Dosage Form

The most common pharmaceutical dosage is the oral solid dosage form, which includes both tablets and capsules. There are many different ways to manufacture these products, starting with the appropriate selection of excipients all the way through the production of the finished product. Ultimately, the successful production of a tablet or capsule is dependent upon… Continue reading An Introduction to Oral Solid Dosage Form

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Introduction to Softgel Manufacturing and Controls

Softgel dosage forms represent a modern take on the traditional tablet product, the most common type of pharmaceutical products produced. In the patient’s hand, a softgel can seem like a simple product not knowing there are numerous complexities that go into its manufacture. But for the manufacturer, without a clear understanding of the science behind… Continue reading Introduction to Softgel Manufacturing and Controls

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Introduction to Tablet Manufacturing by the Direct Compression Process

Solid oral dosage forms such as tablets and capsules represent the most common type of pharmaceutical products produced. In the patient’s hand, a tablet can seem like a simple product not knowing there are numerous complexities that go into its manufacture. But for the manufacturer, without a clear understanding of the science behind the ingredients… Continue reading Introduction to Tablet Manufacturing by the Direct Compression Process

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Equipment Qualification in the GxP Environment

Whether your operation is covered by GMP, GLP, or GCP, there is a regulatory requirement to ensure that all equipment used has been properly demonstrated and documented to be functioning properly. Commonly referred to as Installation Qualification, Operational Qualification, and Performance Qualification. IQ/OQ/PQ provides the framework under which this process can be appropriately performed. Overlooking… Continue reading Equipment Qualification in the GxP Environment

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Introduction to Product Claims Development and Support

Differentiating claims are often key to successful OTC and CPG products. Consumer awareness of products is based on these labels and advertising claims that need to be both consumer meaningful and grounded in adequate scientific support. Agencies like the US-FDA, the Federal Trade Commission (FTC), and even TV networks have established requirements and guidelines on… Continue reading Introduction to Product Claims Development and Support

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We’ve rebranded! CfPA is now COBBLESTONE